TECHNOLOGY
Problem
Intoxications, systemic infections or autoimmune diseases are clinical conditions caused by circulation of disease-causing factors in the blood stream. Often, the most direct way of cure would be the specific removal of these molecules
State of the Art
The selective and efficient removal of large compounds such as bacterial toxins, antibodies or cytokines is still challenging through conventional blood purification, which use filters or adsorber cartridges.
Solution
After years of research, we have found a solution to that problem: HemoSystem allows multi-target precision medicine blood purification at ultra-high efficiency and selectivity using magnetic beads.
Magnetic Sorbent Beads
The non-toxic HemoBeads are the base of our technology. They contain an ultra-magnetic core, a non-sticky polymer and affinity binders that only attach to the desired compounds. By using different binders, the beads can target various targets.
Blood Purification
In the HemoDevice which is similar to a dialysis machine, the sorbent beads are mixed with the patient’s blood and bind to the target compounds. Because fresh beads are provided continuously, saturation is avoided.
Magnetic Separation
Beads and bound targets are highly efficiently removed from the blood in a magnetic cartridge, before the blood flows back to the patient. This makes sure that the beads are not entering the patient’s body.
INTRODUCING THE HEMOSYSTEM
01
HemoSorbent
Sterile single use suspension of small magnetic sorbent beads (HemoBeads).The HemoBeads are supplied in a pre-filled syringe.
02
HemoDevice
Active reusable medical device similar to a dialysis machine. The HemoDevice unit is intended for the safe administration and retrieval of the HemoBeads from an extracorporeal blood circuit.
03
HemoDisposable
Sterile single use disposable tubing set that is inserted into the HemoDevice unit.
PUBLICATIONS
Synthesis and Covalent Surface Functionalization of Nonoxidic Iron Core−Shell Nanomagnets.
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